Junhui Li

2 months ago | nature.com | Shahid Banday |Alok Mishra |Tianyi Ye |Junhui Li |Jason T. Yustein |Michelle Kelliher | +2 more

AbstractEwing sarcoma (ES) is an aggressive bone cancer driven by the oncogenic fusion-protein EWSR1::FLI1, which is not present in normal cells and is therefore an attractive therapeutic target. However, as a transcription factor, EWSR1::FLI1 is considered undruggable. Factors that promote EWSR1::FLI1 expression, and thus whose inhibition would reduce EWSR1::FLI1 protein levels and function, are potential drug targets.

Feb 29, 2024 | mdpi.com | Yujie Liang |Yi Liang |Xiaoge Wang |Junhui Li

1. IntroductionSynthetic aperture radar (SAR) is widely mounted on aerial platforms such as airplanes due to its weather-independent and day-and-night sensing capability to obtain high-resolution images over long distances [1,2,3,4,5]. It has been applied in various fields, such as environmental monitoring, ground surveying, and target detection.

Nov 21, 2023 | mdpi.com | Jing Zhao |Ning Liu |Junhui Li |Xi Guo

1. IntroductionWith the widespread production and use of various hazardous materials (hazmat) in modern society, the road transportation of hazmat has become an important economic activity. Hazmat road transportation is highly concerning due to its substantial impact on social safety. As a typical type of hazmat, explosives have chemical instability and explosiveness.