Kamala Vanarsa

Jul 22, 2024 | digitalcommons.library.tmc.edu | Kamala Vanarsa |Jessica M. Castillo |Long Wang |Kyung Lee

BACKGROUND: Bladder cancer (BC) is among the most common cancers diagnosed in men in the USA. The current gold standards for the diagnosis of BC are invasive or lack the sensitivity to correctly identify the disease. METHODS: An aptamer-based screen analyzed the expression of 1317 proteins in BC compared to urology clinic controls. The top hits were subjected to systems biology analyses. Next, 30 urine proteins were ELISA-validated in an independent cohort of 68 subjects.