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2 weeks ago | 
digitalcommons.library.tmc.edu | Kyung Lee
AbstractBackground: One of the most promising approaches for early and more precise disease prediction and diagnosis is through the inclusion of proteomics data augmented with clinical data. Clinical proteomics data is often characterized by its high dimensionality and extremely limited sample size, posing a significant challenge when employing machine learning techniques for extracting only the most relevant information.
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3 weeks ago | 
ascpt.onlinelibrary.wiley.com | Catherine Chanfreau-Coffinier |Kevin A Friede |Mary E. Plomondon |Kyung Lee
WHAT IS THE CURRENT KNOWLEDGE ON THE TOPIC? Patients carrying CYP2C19 loss-of-function alleles have been shown to have an increased risk of major adverse cardiac events (MACE) following percutaneous coronary intervention for the indication of acute coronary syndrome (ACS). WHAT QUESTION DID THIS STUDY ADDRESS?
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1 month ago | 
tandfonline.com | Kyung Lee |Juho Bai
ABSTRACTThis study examines the impact of the Video Assistant Referee (VAR) on professional football using data from 61,395 matches across 24 leagues in 15 countries between 2012 and 2022. Employing a staggered Difference-in-Differences approach, we assess how VAR influences the number of goals scored, goal timing, and disciplinary actions. Our comprehensive match-level analysis captures nuanced effects that aggregated data might overlook.
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1 month ago | 
nature.com | Meghana S. Pagadala |Tori Anglin-Foote |Nai-Chung Chang |Kyung Lee |Tyler M Seibert |Julie Lynch | +1 more
AbstractGiven the various roles of testosterone in men’s health, we conducted a multi-ancestral genetic analysis of total testosterone, free testosterone, SHBG, and hypogonadism in men within the Million Veteran Program (MVP). Here we identified 157 significant testosterone genetic variants, of which 8 have significant ancestry-specific associations. These variants implicate several genes, including SERPINF2, PRPF8, BAIAP2L1, SHBG, PRMT6, and PPIF, related to liver function.
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2 months ago | 
mdpi.com | Min Suk Chae |Jin-Oh Jeong |Kyung Lee |Wonwoo Jeong
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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2 months ago | 
onlinelibrary.wiley.com | Kyung Lee |Jeong Eun Jeon |Mi Hyun Lee |Jooyoung Lee
1 Introduction Shift work follows non-standard working hours (e.g., from 7:00 a.m. to 6:00 p.m.) that often misalign natural circadian rhythms, approximately a 24 h wake–sleep cycle (Torquati et al. 2019). Shift work is essential for providing adequate services and productivity in several workplaces, including healthcare, transportation and protective services (Brown et al. 2020).
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Nov 21, 2024 | 
ami.info.umfcluj.ro | Ki-Byung Lee |Kyung Lee |Sungsoo Hong |Hyunwoo CHOO
Abstract Early diagnosis of sepsis is crucial in clinical practice. Several studies have proposed sepsis prediction models to forecast the onset of sepsis in hospitals. However, validation of prediction models for community-onset sepsis, which is sepsis developed before admission to the hospital, is insufficient. This study investigates the relationship between the in-hospital prediction model scores and community-onset sepsis.
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Nov 21, 2024 | 
ami.info.umfcluj.ro | Ki-Byung Lee |Sungsoo Hong |Hyunwoo CHOO |Kyung Lee
Abstract In production settings, deep learning models often rely on fixed thresholds. This study investigates whether using varying thresholds over time enhances predictive accuracy and clinical utility, especially for early sepsis prediction. We retrospectively analyzed EMR data from Hallym University Chuncheon Sacred Heart Hospital (2018-2022), excluding patients aged under 18 or without vital signs.
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Nov 14, 2024 | 
journals.plos.org | Kyung Lee |Min-Young Song |Sora Lee |Jinsun Park
The funding statement for this paper is incorrect. The correct funding statement is as follows: This research was supported by a grant from the National Research Foundation (grant number 2022R1A2C2008867), awarded to Prof. Weon Kim. Reference1. Lee KH, Song M- Y, Lee S, Park J, Kang JH, Cho H, et al. (2024) Nitric oxide releasing nanofiber stimulates revascularization in response to ischemia via cGMP-dependent protein kinase. PLoS ONE 19(5): e0303758. https://doi.org/10.1371/journal.pone.0303758.
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Oct 20, 2024 | 
onlinelibrary.wiley.com | Sun-Young Kim |Kyung Lee |Jeong Eun Jeon |Jin You
1 INTRODUCTION Approximately 10% of the adult population is believed to suffer from chronic insomnia disorder (CID) lasting for > 3 months, and another 20% experience occasional insomnia symptoms. Individuals with CID often experience daytime difficulties that impair professional and social functioning as well as increase the likelihood of accidents (Morin & Jarrin, 2022).
