Kandy Napan

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Transcriptional changes consistent with altered neuronal differentiation, angiogenesis, and tumor plasticity induced in human subpallial telencephalic organoid-glioblastoma chimeras.

May 12, 2023 | biorxiv.org | Simone Chiola |Jingye Yang |Kandy Napan |Qiju Huang

New Results doi: https://doi.org/10.1101/2023.05.11.540229 AbstractGlioblastoma multiforme (GBM) is one of the most aggressive and therapy-resistant brain tumors prevalent in both adults and children. Despite extensive research to understand GBM pathology, it remains unclear how neural cells in the human brain interact with GBM cells to support their brain propagation and therapy resistance and whether GBM cells exert any influence on the properties of human neural cells.
Transcriptional changes consistent with impaired neuronal differentiation, angiogenesis, and tumor plasticity induced in human subpallial telencephalic organoid-glioblastoma chimeras.

May 11, 2023 | biorxiv.org | Simone Chiola |Jingye Yang |Kandy Napan |Qiju Huang

New Results doi: https://doi.org/10.1101/2023.05.11.540229 AbstractGlioblastoma multiforme (GBM) is one of the most aggressive and therapy-resistant brain tumors prevalent in both adults and children. Despite extensive research to understand GBM pathology, it remains unclear how neural cells in the human brain interact with GBM cells to support their brain propagation and therapy resistance and whether GBM cells exert any influence on the properties of human neural cells.

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