Simone Chiola

Nov 7, 2023 | frontiersin.org | Zhong-Wei Zhou |Simone Chiola |Xiaoqian Liu

1 IntroductionMicrocephaly in human is a developmental disorder that results in a reduction of head size such that head circumference is three standard deviations lower than the mean for a human of the same age and sex. A major cause of microcephaly is an impaired development of the brain (microencephaly) (Kaindl et al., 2010; Gilmore and Walsh, 2013; Alcantara and O'Driscoll, 2014; Jayaraman et al., 2018; Phan and Holland, 2021; Zaqout and Kaindl, 2022), which is the focus of this treatise.

May 12, 2023 | biorxiv.org | Simone Chiola |Jingye Yang |Kandy Napan |Qiju Huang

New Results doi: https://doi.org/10.1101/2023.05.11.540229 AbstractGlioblastoma multiforme (GBM) is one of the most aggressive and therapy-resistant brain tumors prevalent in both adults and children. Despite extensive research to understand GBM pathology, it remains unclear how neural cells in the human brain interact with GBM cells to support their brain propagation and therapy resistance and whether GBM cells exert any influence on the properties of human neural cells.

May 11, 2023 | biorxiv.org | Simone Chiola |Jingye Yang |Kandy Napan |Qiju Huang

New Results doi: https://doi.org/10.1101/2023.05.11.540229 AbstractGlioblastoma multiforme (GBM) is one of the most aggressive and therapy-resistant brain tumors prevalent in both adults and children. Despite extensive research to understand GBM pathology, it remains unclear how neural cells in the human brain interact with GBM cells to support their brain propagation and therapy resistance and whether GBM cells exert any influence on the properties of human neural cells.