Kanon Jatuworapruk

Mar 7, 2024 | onlinelibrary.wiley.com | Kanon Jatuworapruk

1 TOPHUS BURDEN IS A MAJOR OUTCOME DOMAIN IN GOUT STUDIES Tophus burden is a crucial outcome domain in gout, the most prevalent inflammatory joint disease in adults worldwide, characterized by the continuous deposition of monosodium urate (MSU) crystals.1 Individuals with gout typically experience recurrent episodes of arthritis (gout flares) during the earlier phase of the disease.

Dec 14, 2023 | nature.com | Kanon Jatuworapruk |Worawit Louthrenoo

For individuals with gout, the treatment options beyond conventional urate-lowering therapies are expanding. Notable advancements in 2023 include developments in uricase therapy, new xanthine oxidase inhibitors, and a class of medications that offer dual benefits for the control of type 2 diabetes mellitus and gout.