Karen Chiswell

Sep 25, 2024 | jamanetwork.com | Stephen Greene |Karen Chiswell |Gary K. Grunwald |Vincenzo B. Polsinelli

Key PointsQuestion  Is a composite score for guideline-directed medical therapy (GDMT) for heart failure with reduced ejection fraction at the time of discharge on a hospital level associated with improved outcomes at lower costs? Findings  In this cohort study including 41 161 patients across 360 hospitals, higher hospital composite GDMT score was associated with lower mortality, lower mortality or rehospitalization, more home time, and lower costs.

Aug 9, 2024 | medrxiv.org | Matthew S. Durstenfeld |C. Larry Hill |Robert M. Clare |Karen Chiswell

AbstractBackground: People with HIV (PWH) are at elevated risk for atherosclerotic cardiovascular disease (ASCVD). Underrepresented racial and ethnic groups (UREGs) with HIV in the southern U.S. are disproportionately affected, yet whether cardiology specialist care for this at-risk group improves blood pressure and lipid control or prevents cardiovascular events is unknown.

Jun 26, 2024 | jamanetwork.com | Daniel Edmonston |Elizabeth A. Lydon |Hillary Mulder |Karen Chiswell

Key PointsQuestion  What patient-level risk factors are associated with inadequate screening and treatment for chronic kidney disease (CKD) among people with type 2 diabetes (T2D)? Findings  In this cohort study of 316 234 participants with T2D, fewer than 25% received guideline-recommended CKD screening, and patient-level factors such as Hispanic ethnicity and comorbid cardiovascular disease were associated with concordance with screening recommendations.

Jun 1, 2024 | jacc.org | Daniel Edmonston |Hillary Mulder |Elizabeth A. Lydon |Karen Chiswell

References1. "National Diabetes Statistics Report". 2020. Accessed July 3, 2024. https://doi.org/https://www.cdc.gov/diabetes/php/data-research/data-statistics/index.html. 2. "Understanding CKD among patients with T2DM: prevalence, temporal trends, and treatment patterns-NHANES. 2007-2012". BMJ Open Diabetes Res Care . 2016;4:e000154. 3. "Kidney disease and increased mortality risk in type 2 diabetes". J Am Soc Nephrol . 2013;24:302-308. 4.

May 16, 2024 | onlinelibrary.wiley.com | Anthony Peters |Robert M. Clare |Karen Chiswell |Josephine Harrington

Introduction Heart failure (HF) with preserved ejection fraction (HFpEF) represents a highly prevalent public health burden, affecting more than 50% of the 6 million patients in the United States with HF.1, 2 Outcomes for patients with HFpEF remain poor with high rates of hospitalization and death along with low quality of life.1-3 Improvements in outcomes are lagging due to limited effective therapies.