Karen Wendt
Author at MoreThanDigital
#PHD Candidate #Editor Sustainable Finance and #SDG Economics Book Series with #Springer Nature #Lecturer, #Systemic Coach,# Keynotes
Articles
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May 26, 2024 |
biorxiv.org | Monica Ness |Thilini Peramuna |Karen Wendt |Jennifer Collins
AbstractNatural product libraries are crucial to drug development, but large libraries drastically increase the time and cost during initial high throughput screens. Here, we developed a method that leverages liquid chromatography-tandem mass spectrometry spectral similarity to dramatically reduce library size, with minimal bioactive loss. This method offers a broadly applicable strategy for accelerated drug discovery with cost reductions, which enable implementation in resource-limited settings.
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