Karl A. Hassan

Sep 4, 2024 | microbiologyresearch.org | Catherine J. Dawson |Karl A. Hassan |Rosmarie Rippka |Amelia Bartczak

Article metrics loading... /content/journal/micro/10.1099/mic.0.001499Download as PowerPoint /deliver/fulltext/micro/170/9/mic001499.html?itemId=/content/journal/micro/10.1099/mic.0.001499&mimeType=html&fmt=ahah References Murray CJL, Ikuta KS, Sharara F, Swetschinski L, Robles Aguilar G et al. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis.

Dec 7, 2023 | frontiersin.org | Sandra Truong |Karl A. Hassan |Ramona Iseppi

1 IntroductionSince their discovery, antibiotics have greatly increased our quality of life, treating infections which were once considered life-threatening. However, our reliance and increased antibiotic usage has contributed to the emergence of several antibiotic resistant bacterial strains. As Staphylococcus aureus is a commensal mucosal organism in almost half the population, our repeated use of antibiotics has inevitably caused the development of multiple methicillin resistant S.

Oct 9, 2023 | nature.com | Liping Li |Francesca L. Short |Karl A. Hassan |Stephanie S. Nagy |Bhumika S. Shah |Nusrat Afrin | +2 more

AbstractConcerns exist that widespread use of antiseptic or disinfectant biocides could contribute to the emergence and spread of multidrug-resistant bacteria. To investigate this, we performed transposon-directed insertion-site sequencing (TraDIS) on the multidrug-resistant pathogen, Acinetobacter baumannii, exposed to a panel of ten structurally diverse and clinically relevant biocides.

Jul 26, 2023 | biorxiv.org | Varsha N Naidu |Bhumika S. Shah |Karl A. Hassan |Ian T. Paulsen

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Feb 9, 2023 | nature.com | Lucie Semenec |Amy Cain |Catherine J. Dawson |Anahit Penesyan |Francesca L. Short |Karl A. Hassan | +1 more

AbstractAcinetobacter baumannii and Klebsiella pneumoniae are opportunistic pathogens frequently co-isolated from polymicrobial infections. The infections where these pathogens co-exist can be more severe and recalcitrant to therapy than infections caused by either species alone, however there is a lack of knowledge on their potential synergistic interactions. In this study we characterise the genomes of A. baumannii and K. pneumoniae strains co-isolated from a single human lung infection.