
Katerina Kouvidi
Articles
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Oct 19, 2023 |
biorxiv.org | Katerina Kouvidi |Chris Grant |Zorana Carter |Declan R Creamer
AbstractMisfolded proteins are usually refolded to their functional conformations or degraded by quality control mechanisms. When misfolded proteins evade quality control, they can be sequestered to specific sites within cells to prevent the potential dysfunction and toxicity that arises from protein aggregation. Btn2 and Hsp42 are compartment-specific sequestrases that play key roles in the assembly of these deposition sites.
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