Katherine M. Sheu

Oct 15, 2024 | cell.com | Katherine M. Sheu |Computational Biosciences |Alexander Hoffmann

Keywords inducible gene expression dynamics single cell trajectory ensembles information theory machine learning macrophage context dependence stimulus-response specificity gene expression trajectories Introduction Macrophages are immune sentinel cells that deploy their diverse functions in response to exposure to pathogens or activating stimuli.1,2 Immune response genes not only differ in the magnitudes of induction but also show distinctive temporal dynamics evident in the gene expression...