Alexander Hoffmann

1 month ago | medium.com | Alexander Hoffmann

Alexander Hoffmann·Follow6 min read·--Losing access to a Yahoo account can be a frustrating and stressful experience, especially if it contains important emails, contacts, or sensitive information. While hacking and unauthorized access to accounts are illegal and unethical, there is a legitimate and ethical way to recover a compromised Yahoo account: by hiring a certified hacker.

2 months ago | biorxiv.org | Eiji Nakamura |Franco Blanchini |Giulia Giordano |Alexander Hoffmann

AbstractCells have the capacity to encode and decode information in the temporal features of molecular signals. Many pathways, for example, generate either sustained or pulsatile responses depending on the context, and such diverse temporal behaviors have a profound impact on cell fate. Here we focus on how molec- ular pathways can convert the temporal features of dynamic signals, in particular how they can convert transient signals into persistent downstream events and vice versa.

Jan 13, 2025 | pubs.rsc.org | Sonja Herres-Pawlis |Tobias Seitz |RWTH Aachen |Marcel Walbeck |Alexander Hoffmann

Electron transfer kinetics of a series of copper complexes with tripodal tetradentate guanidine quinolinyl ligands† Copper complexes of tripodal ligands have been used as model systems for electron transfer proteins for decades, displaying a broad range of electron self-exchange rates. We herein report a group of six tripodal tetradentate triarylamine ligands which display a varying number of guanidine and 2-methylquinolinyl moieties.

Jan 8, 2025 | thelancet.com | Alexander Hoffmann |Gilbert S. Omenn |Diego R. Mazzotti

ArticlesVolume 7, Issue 1e35-e43Open access aDepartment of Biomedical Informatics, Medical School, Harvard University, Boston, MA, USA bDepartment of Internal Medicine, University of Texas at Southwestern, Dallas, TX, USA cOffice of Informatics and Information Technology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA dComputational Medicine and Bioinformatics, Internal Medicine, Human Genetics, Environmental Health, University of Michigan, Ann Arbor,...

Jan 7, 2025 | science.org | Dana M. Cairns |Carolina Chávez |Kelly Lin |Alexis Malveaux |Quen Cheng |Alexander Hoffmann | +2 more

Research ArticleINNATE IMMUNITY Access the full articleView all access options to continue reading this article. Supplementary MaterialsMDAR Reproducibility ChecklistREFERENCES AND NOTES1K. M. Sheu, A. Hoffmann, Functional hallmarks of healthy macrophage responses: Their regulatory basis and disease relevance. Annu. Rev. Immunol. 40, 295–321 (2022). 2M. G. Netea, J. Domínguez-Andrés, L. B. Barreiro, T. Chavakis, M. Divangahi, E. Fuchs, L. A. B. Joosten, J. W. M. van der Meer, M. M. Mhlanga, W. J. M. Mulder, N. P. Riksen, A.