Katherine Pak

1 month ago | acsjournals.onlinelibrary.wiley.com | Chun Chao |Hui Zhou |Dov Shalman |Katherine Pak

DATA AVAILABILITY STATEMENT Anonymized data that support the findings of this study may be made available from the corresponding author on reasonable request from qualified researchers with documented evidence of training for human subjects protections.

Jan 19, 2025 | biorxiv.org | Sahana Jayaraman |Katherine Pak |Iago Pinal-Fernandez |Jon Musai

AbstractObjectives: In dermatomyositis patients with anti-Mi2 autoantibodies, autoantibodies can enter muscle cells, leading to the aberrant expression of genes normally repressed by the Mi2/nucleosome remodeling and deacetylation (NuRD) complex. However, the mechanism by which autoantibodies interfere with Mi2/NuRD function remains unclear.