Kathy L. Lindquist

Jun 5, 2024 | jneurosci.org | Christopher Driskill |Jessica Childs |John O’Brien |Kathy L. Lindquist

Vagus Nerve Stimulation (VNS) Modulates Synaptic Plasticity in the Infralimbic Cortex via Trk-B Receptor Activation to Reduce Drug-Seeking in Male Rats Christopher M. Driskill, Jessica E. Childs, Aarron J. Phensy, Sierra R. Rodriguez, John T. O’Brien, Kathy L. Lindquist, Aurian Naderi, Bogdan Bordieanu, Jacqueline F. McGinty, Sven Kroener Journal of Neuroscience 5 June 2024, 44 (23) e0107242024; DOI: 10.1523/JNEUROSCI.0107-24.2024

May 2, 2024 | jneurosci.org | Christopher Driskill |Jessica Childs |John O’Brien |Kathy L. Lindquist

AbstractDrugs of abuse cause changes in the prefrontal cortex (PFC) and associated regions that impair inhibitory control over drug-seeking. Breaking the contingencies between drug-associated cues and the delivery of the reward during extinction learning reduces relapse. Vagus nerve stimulation (VNS) has previously been shown to enhance extinction learning and reduce drug-seeking.