Katrina Thornber

London

Editorial Assistant at EMJ- European Medical Journal

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emjreviews.com

Articles

Three-Year Clinical Outcomes of IVBT for Multilayer Drug-eluting In-stent Restenosis

21 hours ago | emjreviews.com | Katrina Thornber

TREATMENT with intravascular brachytherapy (IVBT) for multilayer drug-eluting in-stent restenosis (DES-ISR) is associated with a lower rate of major adverse cardiac events (MACE) at three years compared to non-IVBT strategies. Multilayer in-stent restenosis (ISR), particularly in patients with multiple layers of drug-eluting stents, remains a significant clinical challenge due to high rates of recurrent adverse cardiac events.
Biomimetic Hydrogels Revolutionise CAR T Cancer Therapy Production

1 day ago | emjreviews.com | Katrina Thornber

NOVEL lymph-node-inspired hydrogels enhance CAR T cell activation and proliferation by 50%, offering a more efficient and cost-effective method for producing this cutting-edge cancer immunotherapy, according to a study published in ACS Applied Materials & Interfaces. CAR T cell therapy, which modifies a patient’s immune cells to target cancer, has revolutionised treatment for certain blood cancers but faces challenges in manufacturing efficiency and cost.
Intensive Blood Pressure Control Cuts Dementia Risk by 15%, Trial Reveals

2 days ago | emjreviews.com | Katrina Thornber

INTENSIVE blood pressure (BP) control in patients with hypertension reduces the risk of all-cause dementia by 15%, according to the CRHCP-3 cluster-randomised trial involving 33,995 individuals in rural China, published in Nature Medicine. Dementia, a leading global cause of disability and death, is projected to affect over 150 million people by 2050, with hypertension identified as a modifiable risk factor.
At-Home Etripamil Reduces Emergency Visits for Supraventricular Tachycardia

4 days ago | emjreviews.com | Katrina Thornber

SELF-ADMINISTERED etripamil, an intranasal calcium channel blocker, significantly reduces emergency department (ED) visits for paroxysmal supraventricular tachycardia (PSVT) by 39% compared to placebo, according to a pooled analysis of the NODE-301 and RAPID randomised clinical trials involving 340 patients. PSVT, characterised by sudden rapid heart rates, often requires urgent medical intervention, with current oral therapies limited by delayed efficacy and safety concerns.
What are the Risk Factors for Late-Onset Epilepsy in Patients with Cognitive Decline?

5 days ago | emjreviews.com | Katrina Thornber

INDIVIDUALS with cognitive decline (dementia or mild cognitive impairment) carrying the APOE4 allele, experiencing early-onset dementia, or having Alzheimer’s disease, Parkinson’s disease, stroke, or severe cognitive impairment face a significantly higher risk of developing late-onset epilepsy (LOE), according to a longitudinal study of 14,685 participants across 39 US Alzheimer’s research centres.
Severe Anxiety in Multiple Sclerosis Linked to Uncinate Fasciculus Lesions

5 days ago | emjreviews.com | Katrina Thornber

HIGHER lesion burden in the uncinate fasciculus (UF), a key brain pathway linking emotional regulation regions, is associated with increased anxiety severity in multiple sclerosis (MS) patients, according to a retrospective case-control study of 372 individuals. MS, an immune-mediated neurological disorder affecting 2.4 million people globally, is frequently accompanied by anxiety, with up to 60% of patients experiencing symptoms.
Smart ECG Shirt Monitors Heart Rate Recovery, Predicts Cardiovascular Risk

1 week ago | emjreviews.com | Katrina Thornber

CONTINUOUS monitoring of heart rate recovery (HRR) using wearable ECG technology can identify individuals at higher risk of cardiovascular and metabolic disorders, achieving an 86% accuracy in risk classification, according to a study published in the IEEE Journal of Health Informatics. HRR, the time it takes for the heart to return to baseline rhythm after exercise, is a key indicator of autonomic nervous system function and cardiovascular health.
Urodynamics Adds No Benefit in Treating Overactive Bladder

1 week ago | emjreviews.com | Katrina Thornber

OVERACTIVE bladder (OAB) affects 12–14% of women in the UK, significantly disrupting their quality of life. Beyond the physical discomfort, the condition affects social and psychological wellbeing, as well as work productivity. In more severe cases, many women avoid employment, 60% avoid leaving their homes, and 50% report avoiding sexual activity. First-line treatments for OAB include lifestyle changes, bladder retraining, pelvic floor exercises, and medication.
How Is Industrial Pollution Impacting Global Respiratory Health?

1 week ago | emjreviews.com | Katrina Thornber

A NEW study analysing the trends in mortality from occupational chronic respiratory diseases (CRD) caused by particulate matter, gases, and fumes (PMGF) highlights both progress and ongoing challenges. Data from the Global Burden of Disease 2021 were extracted to assess the age-standardised mortality rate of PMGF-attributed CRDs, using joinpoint regression to examine global trends from 1990–2021, and age-period-cohort models to analyse the impact of age, period, and cohort effects.
Disadvantaged Neighbourhoods and Breast Cancer Mortality Among Black Women

1 week ago | emjreviews.com | Katrina Thornber

A NEW study from researchers based in the US has found that Black women living in economically deprived neighbourhoods face a significantly higher risk of dying from breast cancer, regardless of their personal lifestyle, treatment received, or stage of diagnosis. The research, published as part of the Black Women’s Health Study (BWHS), analysed data from 2,290 Black women diagnosed with stages I to III breast cancer.