Kaylee Rosenberger

Jun 20, 2024 | biorxiv.org | Kaylee Rosenberger |Lauren A. Vanderlinden |Jun Inamo |Hope A Townsend

AbstractBackground: Understanding genetic underpinnings of immune-mediated inflammatory diseases is crucial to improve treatments. Single-cell RNA sequencing (scRNA-seq) identifies cell states expanded in disease, but often overlooks genetic causality due to cost and small genotyping cohorts. Conversely, large genome-wide association studies (GWAS) are commonly accessible.