Ken Yamazaki

Jul 8, 2024 | nature.com | Yaseen A. Almehmadi |Kirsten Christensen |Ken Yamazaki |Nandini J. Guzman

AbstractThree-dimensional nitrogen-rich bridged ring systems are of great interest in drug discovery owing to their distinctive physicochemical and structural properties. However, synthetic approaches towards N–N-bond-containing bridged heterocycles are often inefficient and require tedious synthetic strategies.

May 1, 2023 | nature.com | Tatiana Rogova |Kirsten Christensen |Fernanda Duarte |Ken Yamazaki

AbstractMolecules that contain a stereogenic phosphorus atom are crucial to medicine, agrochemistry and catalysis. While methods are available for the selective construction of various chiral organophosphorus compounds, catalytic enantioselective approaches for their synthesis are far less common.