Kevin Maringer

2 months ago | nature.com | Matthew Sherwood |Thiago G Mitsugi |Carolini Kaid |Brandon Coke |Mayana Zatz |Kevin Maringer | +1 more

AbstractBrain tumours disproportionately affect children and are the largest cause of paediatric cancer-related death. Novel therapies that engage the immune system, such as oncolytic viruses (OVs), hold great promise and are desperately needed. Zika virus (ZIKV) infects and destroys aggressive cells from multiple paediatric central nervous system (CNS) tumours. Despite this, the molecular mechanisms underpinning this response are largely unknown.