Kofi Deh

Mar 5, 2024 | onlinelibrary.wiley.com | Guannan Zhang |Kofi Deh |Charles H. Cunningham |Hijin Park

Corresponding Author Kayvan R. Keshari PhD Department of Radiology, Memorial Sloan Kettering Cancer Center, New York City, New York, USA Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York City, New York, USA Address reprint requests to: K.R.K., Department of Radiology and Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York City, NY 10065, USA. E-mail: [email protected] for more papers by this author

Jun 19, 2023 | analyticalsciencejournals.onlinelibrary.wiley.com | Guannan Zhang |Quinlan Cullen |Marjan Berishaj |Kofi Deh

Abstract Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths. Imaging plays a crucial role in the early detection of HCC, although current methods are limited in their ability to characterize liver lesions. Most recently, deuterium metabolic imaging (DMI) has been demonstrated as a powerful technique for the imaging of metabolism in vivo. Here, we assess the metabolic flux of [6,6′-2H2] fructose in cell cultures and in subcutaneous mouse models at 9.4 T.