Quinlan Cullen

Jun 19, 2023 | analyticalsciencejournals.onlinelibrary.wiley.com | Guannan Zhang |Quinlan Cullen |Marjan Berishaj |Kofi Deh

Abstract Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths. Imaging plays a crucial role in the early detection of HCC, although current methods are limited in their ability to characterize liver lesions. Most recently, deuterium metabolic imaging (DMI) has been demonstrated as a powerful technique for the imaging of metabolism in vivo. Here, we assess the metabolic flux of [6,6′-2H2] fructose in cell cultures and in subcutaneous mouse models at 9.4 T.