Koji Iwamoto

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RasGEFX triggers spontaneous Ras excitation with RasGEFB/M/U for random cell migration

Aug 14, 2023 | biorxiv.org | Koji Iwamoto |Satomi Matsuoka |Masahiro Ueda

AbstractExcitable systems of eukaryotic chemotaxis can generate asymmetric signals of Ras-GTP-enriched domains spontaneously to drive random cell migration without guidance cues. The molecules responsible for the spontaneous signal generation remain elusive.

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