Kouya Shiraishi

Aug 6, 2024 | digitalcommons.library.tmc.edu | Jianxin Shi |Kouya Shiraishi |Jiyeon Choi |Keitaro Matsuo

AbstractLung adenocarcinoma is the most common type of lung cancer. Known risk variants explain only a small fraction of lung adenocarcinoma heritability. Here, we conducted a two-stage genome-wide association study of lung adenocarcinoma of East Asian ancestry (21,658 cases and 150,676 controls; 54.5% never-smokers) and identified 12 novel susceptibility variants, bringing the total number to 28 at 25 independent loci.

May 26, 2023 | nature.com | Jianxin Shi |Kouya Shiraishi |Jiyeon Choi |Tzu-Yu Chen |Juncheng Dai |Rayjean J. Hung | +61 more

AbstractLung adenocarcinoma is the most common type of lung cancer. Known risk variants explain only a small fraction of lung adenocarcinoma heritability. Here, we conducted a two-stage genome-wide association study of lung adenocarcinoma of East Asian ancestry (21,658 cases and 150,676 controls; 54.5% never-smokers) and identified 12 novel susceptibility variants, bringing the total number to 28 at 25 independent loci.

Feb 16, 2023 | nature.com | Kouya Shiraishi

AbstractBackgroundWe investigated the utility of a molecular classifier tool and genetic alterations for predicting prognosis in Japanese patients with endometrial cancer. MethodsA total of 1029 patients with endometrial cancer from two independent cohorts were classified into four molecular subtype groups. The primary and secondary endpoints were relapse-free survival (RFS) and overall survival (OS), respectively.