Kuang Lin

Feb 6, 2024 | biorxiv.org | Sam Morris |Kuang Lin |Iona Y. Millwood |Canqing Yu

AbstractBackgroundPathogens have been one of the primary sources of natural selection affecting modern humans. The footprints of historical selection events ("selective sweeps") can be detected in the genomes of present-day individuals. Previous analyses of 629 samples from the 1000 Genomes Project suggested that an ancient coronavirus epidemic ~20,000 years ago drove multiple selective sweeps in the ancestors of present-day East Asians, but not in other worldwide populations.