L. Heide

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Discovery of new molecular hybrid derivatives with coumarin scaffold bearing pyrazole/oxadiazole moieties: Molecular docking, POM analyses, in silico pharmacokinetics and in vitro antimicrobial evaluation with identification of potent antitumor pharmacoph

Sep 5, 2024 | sciencedirect.com | Chao Lin |Geng Sun |Irina Gorbunova |L. Heide

The advent of antibiotics resistance has become a significant concern in global public health in recent years. Global estimates indicate that over 700,000 individuals succumb to antimicrobial resistance each year [1]. Romania ranks first among the leading nations with a high prevalence of antimicrobial/antibiotic use, which favours to the development and spreading of drug-resistant bacteria [2].

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