Laszlo Mechtler

Nov 21, 2024 | headachejournal.onlinelibrary.wiley.com | Jessica Ailani |Richard Lipton |Andrew Blumenfeld |Laszlo Mechtler

AE adverse event ALT alanine aminotransferase AST aspartate aminotransferase CGRP calcitonin gene-related peptide CI confidence interval ECG electrocardiogram EM episodic migraine ICHD-3 International Classification of Headache Disorders, third edition PRN as needed QD once daily SD standard deviation TEAE treatment-emergent AE ULN upper limit of normal INTRODUCTION Migraine is a debilitating neurological disease that impacts ~1.1 billion individuals worldwide, with >90% of those individuals...

Aug 28, 2023 | journals.sagepub.com | Richard Lipton |Laszlo Mechtler |Jennifer W McVige |Julia Hauprich MA

IntroductionMigraine attacks can substantially impact health-related quality of life (HRQoL), including performance of daily activities and both physical and emotional functioning (1–3). The impact of migraine on physical, social and emotional function can be experienced during attacks, as well as in the interictal period (i.e. the time between attacks) (4).