Laura Cox

Jul 9, 2024 | onlinelibrary.wiley.com | Laura Cox |Vijay K. Kuchroo

The gut microbiome is a diverse collection of bacteria, fungi, and viruses that have coevolved with the immune system. The microbiome plays a central role in shaping immunologic development as well as regulating other physiologic processes, including metabolic and neurologic functions.

Oct 2, 2023 | nature.com | Laura Cox

Human aging is associated with increased rates of many cardiac diseases and tissue remodeling. However, disentangling the mechanisms that underlie normal heart aging from disease processes is challenging. A study now addresses this gap by investigating healthy primate cardiac aging and provides evidence that SIRT2 signaling may regulate cardioprotective effects. Heart disease is the most common cause of death, affecting about 5% of adults older than 20 years of age.

Jun 22, 2023 | nature.com | Stephen Walker |Laura Cox |Anthony Atala

AbstractThe human airways are complex structures with important interactions between cells, extracellular matrix (ECM) proteins and the biomechanical microenvironment. A robust, well-differentiated in vitro culture system that accurately models these interactions would provide a useful tool for studying normal and pathological airway biology.