Anthony Atala

Jan 16, 2025 | digitalcommons.library.tmc.edu | Robert Jordan |Anthony Atala |Stephanie L Ford-Scheimer |Rodolfo M Alarcon

Keywords Antiviral Agents, Drug Discovery, Biological Assay, 3D tissue models, SARS-CoV-2, antiviral drug discovery, body-on-a-chip, human pluripotent stem cells (hPSCs), induced pluripotent stem cells (iPSCs), microphysiological systems (MPS), organ-on-a-chip, organoid, tissue-derived stem cells Abstract The National Center for Advancing Translational Sciences (NCATS) Assay Guidance Manual (AGM) Workshop on 3D Tissue Models for Antiviral Drug Development, held virtually on 7-8 June 2022,...

Oct 17, 2024 | onlinelibrary.wiley.com | Sang Lee |Wonwoo Jeong |Anthony Atala

Conflict of Interest The authors declare no conflict of interest. References 1a) , , , , Neuron 1990, 5, 527; b) , , FASEB J. 1994, 8, 378. 2, , , , , , J. Biomater. Sci. Polym. Ed. 1996, 8, 63. 3a) , , Anat. Rec. A Discov. Mol. Cell Evol. Biol. 2003, 272, 491; b) , , , , , Anat. Rec. A Discov. Mol. Cell Evol. Biol. 2003, 272, 497. 4, , , , , , , , , , , , , Nat. Biotechnol. 2007, 25, 100. 5, , , Tissue Eng Regen Med 2016, 13, 647.

Sep 24, 2024 | nature.com | Anthony Atala

AbstractDent disease type 1 is caused by changes in the chloride voltage-gated channel 5 (CLCN5) gene on chromosome X, resulting in the lack or dysfunction of chloride channel ClC-5. Individuals affected by Dent disease type 1 show proteinuria and hypercalciuria.

Aug 13, 2024 | nature.com | Anthony Atala

AbstractNatural killer (NK) cells are an important first-line of defense against malignant cells. Because of the potential for increased cancer risk from astronaut exposure to space radiation, we determined whether microgravity present during spaceflight affects the body’s defenses against leukemogenesis.

May 1, 2024 | journals.plos.org | Ana I. Gonçalves |Márcia T. Rodrigues |Sang-Jin Lee |Anthony Atala

Loading metrics Errors were made during the preparation of Fig 2 which resulted in the erroneous duplication of the following panels: hAFSC 14 days EGF (incorrect panel) and hAFSC 14 days TGF-β (correct panel) hAFSC 21 days medium B (incorrect panel) and hAFSC 21 days TGF-β (correct panel) hASC 21 days TGF-β (correct panel) and hASC 28 days medium A (incorrect panel) With this correction, the authors provide a corrected version of Fig 2 as well as the original underlying representative images...