Lauren F. Sestito

Feb 24, 2023 | science.org | Nisarga Paul |Lauren F. Sestito |Liang Yi

LATEST NEWS AbstractOogenesis is influenced by multiple environmental factors. In the fruit fly, Drosophila melanogaster, nutrition and mating have large impacts on an increase in female germline stem cells (GSCs). However, it is unclear whether these two factors affect this GSC increase interdependently. Here, we report that dietary sugars are crucial for the GSC increase after mating.

Feb 24, 2023 | science.org | Nisarga Paul |Lauren F. Sestito |Liang Yi

LATEST NEWS AbstractCells sense a wide variety of signals and respond by adopting complex transcriptional states. Most single-cell profiling is carried out today at cellular baseline, blind to cells’ potential spectrum of functional responses. Exploring the space of cellular responses experimentally requires access to a large combinatorial perturbation space.

Feb 24, 2023 | science.org | Nisarga Paul |Lauren F. Sestito |Liang Yi

LATEST NEWS AbstractThe charge transport properties of conjugated polymers are commonly limited by the energetic disorder. Recently, several amorphous conjugated polymers with planar backbone conformations and low energetic disorder have been investigated for applications in field-effect transistors and thermoelectrics.

Feb 24, 2023 | science.org | Nisarga Paul |Lauren F. Sestito |Liang Yi |Yang Zhang

LATEST NEWS Abstractvan der Waals (vdW) heterostructures formed by two-dimensional (2D) magnets and semiconductors have provided a fertile ground for fundamental science and spintronics.

Feb 24, 2023 | science.org | Nisarga Paul |Lauren F. Sestito |Liang Yi |Dan Wang

LATEST NEWS AbstractConsecutive guanine RNA sequences can adopt quadruple-stranded structures, termed RNA G-quadruplexes (rG4s). Although rG4-forming sequences are abundant in transcriptomes, the physiological roles of rG4s in the central nervous system remain poorly understood. In the present study, proteomics analysis of the mouse forebrain identified DNAPTP6 as an RNA binding protein with high affinity and selectivity for rG4s.