Leah M. Mayo

Jan 30, 2024 | biorxiv.org | Saptarnab Naskar |Leah M. Mayo |Irene Perini |Luis E. Rosas-Vidal

AbstractMaladaptive fear generalization is one of the hallmarks of trauma-related disorders. The endocannabinoid 2-arachidonoylglycerol (2-AG) is crucial for modulating anxiety, fear, and stress adaptation but its role in balancing fear discrimination versus generalization is not known.