Lee Ohayon

Dec 20, 2023 | jbc.org | David Gau |Morgan M.C. Ricci |Andrew Orenberg |Lee Ohayon

ABSTRACTMembrane poly-phosphoinositides (PPIs) are lipid-signaling molecules that undergo metabolic turnover and influence a diverse range of cellular functions. PPIs regulate the activity and/or spatial localization of a number of actin-binding proteins (ABPs) through direct interactions; however, it is much less clear whether ABPs could also be an integral part in regulating PPI signaling.