Leighton J Payne

Dec 11, 2024 | nature.com | Haidai Hu |Philipp F. Popp |Aritz Roa-Eguiara |Nicole R. Rutbeek |Leighton J Payne |Dorentina Humolli | +8 more

AbstractZorya is a recently identified and widely distributed bacterial immune system that protects bacteria from viral (phage) infections. Three Zorya subtypes have been discovered, each containing predicted membrane-embedded ZorAB complexes paired with soluble subunits that differ among Zorya subtypes, notably ZorC and ZorD in type I Zorya systems1,2.

Jan 30, 2024 | biorxiv.org | Thomas Hughes |Peter C. Fineran |Simon Jackson |Leighton J Payne

AbstractBacteria and archaea typically have multiple defence systems that protect them against viral predation. Recently, many new defence systems have been discovered, yet the full scope of the prokaryotic pan-immune system remains to be determined. In this study, we observed that many multi-gene defence systems have additional genes nested or "embedded" within them.