Leila R Hill

Oct 4, 2023 | pubs.rsc.org | Andrew Hall |Amy Robertson |Robert Baker |Leila R Hill

Significant cell uptake of Gd(iii)-diphenylphosphoryl-diphenylphosphonium complexes: evidence for a new conformationally-dependent tumour cell targeting vector† The synthesis, characterisation, and tumour cell uptake of six novel Gd(III)-diphenylphosphoryl-diphenylphosphonium complexes are reported. The propyl-linked Gd(III) complexes can accumulate inside human glioma cells at prodigious levels, approaching 1200%, over the parent triphenylphosphonium salts.