Libo Jiang

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Site-selective superassembly of biomimetic nanorobots enabling deep penetration into tumor with stiff stroma - Nature Communications

Aug 2, 2023 | nature.com | Runhao Zhang |Pu Chen |Zhen Gu |Libo Jiang

AbstractChemotherapy remains as the first-choice treatment option for triple-negative breast cancer (TNBC). However, the limited tumor penetration and low cellular internalization efficiency of current nanocarrier-based systems impede the access of anticancer drugs to TNBC with dense stroma and thereby greatly restricts clinical therapeutic efficacy, especially for TNBC bone metastasis.

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