Lifestyle study

Sep 20, 2024 | nature.com | Shannon L. Risacher |Paula J Bice |Jared Brosch |Kelley Faber |Martin R Farlow |Tatiana Foroud | +29 more

AbstractDetermining the genetic architecture of Alzheimer’s disease pathologies can enhance mechanistic understanding and inform precision medicine strategies. Here, we perform a genome-wide association study of cortical tau quantified by positron emission tomography in 3046 participants from 12 independent studies. The CYP1B1-RMDN2 locus is associated with tau deposition.

Jul 10, 2024 | nature.com | Konstantinos Poulakis |Giovanni Volpe |Daniel R. Ferreira |Eric C Westman |Australian Imaging |Lifestyle study

Correction to: Nature Communications https://doi.org/10.1038/s41467-022-32202-6, published online 5 August 2022The original version of this Article contained an error in Tables 1, 3 and Supplementary Table S7. In Table 1, the correct version of the 2nd row of the 1st column in both the Discovery dataset and Validation dataset states ‘females’ instead of the original, incorrect ‘males’.