Limamanen Phom

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Sequestration of oxidative is necessary but not sufficient enough to conclude dopaminergic neuroprotective efficacy of curcumin: Insights from ALSS Drosophila Parkinson disease model

Sep 19, 2024 | biorxiv.org | Priyanka Modi |Sarat Chandra Yenisetti |Limamanen Phom

AbstractTurmeric is a centuries-old ethnomedicine in Asia. Previously our laboratory demonstrated in the adult life stage-specific (ALSS) Drosophila model of Parkinson disease (PD) that Curcumin (K)-mediated dopaminergic (DAergic) neuroprotection is absent in the transition stage of adult life during which late-onset neurodegenerative disorders like PD sets-in, suggesting its limitation as a therapeutic agent.

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