Lior Pachter

Mar 8, 2024 | liorpachter.wordpress.com | Lior Pachter

In a Tablet Magazine article titled “How the Gaza Ministry of Health Fakes Casualty Numbers” posted on March 6, 2024, Professor of Statistics and Data Science Abraham Wyner from the Wharton School at the University of Pennsylvania argues that statistical analysis of the casualty numbers reported by the Gaza Ministry of Health is “highly suggestive that a process unconnected or loosely connected to reality was used to report the numbers”.

Feb 26, 2024 | liorpachter.wordpress.com | Lior Pachter

The All of Us Research Program, whose mission is to “to accelerate health research and medical breakthroughs, enabling individualized prevention, treatment, and care for all of us”, recently published a flagship paper in Nature on “Genomic Data in the All of Us Research Program“. This is a review of Figure 2 from the paper (referred to below as AoURFig2). BackgroundThe first U.S. Census that commenced on August 2, 1790 included a record of the race of individuals.

Dec 9, 2023 | biorxiv.org | Delaney Sullivan |Lior Pachter

AbstractNext-generation sequencing libraries are constructed with numerous synthetic constructs such as sequencing adapters, barcodes, and unique molecular identifiers. Such sequences can be essential for interpreting results of sequencing assays, and when they contain information pertinent to an experiment, they must be processed and analyzed. We present a tool called splitcode, that enables flexible and efficient parsing, interpreting, and editing of sequencing reads.

Nov 17, 2023 | biorxiv.org | Laura Luebbert |Chi Khanh Hoang |Manjeet Kumar |Lior Pachter

AbstractEukaryotic linear motifs (ELMs), or Short Linear Motifs (SLiMs), are protein interaction modules that play an essential role in cellular processes and signaling networks and are often involved in diseases like cancer. The ELM database is a collection of manually curated motif knowledge from scientific papers. It has become a crucial resource for cataloging motif biology and recognizing candidate ELMs in novel amino acid sequences.

Apr 1, 2023 | biorxiv.org | Delaney Sullivan |Lior Pachter

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