Lisa A. Maier

2 months ago | nature.com | Lucie Lebreuilly |Samantha Samson |Anne Grießhammer |Lisa A. Maier |Thierry Naas |Didier Rognan | +2 more

AbstractThe increasing incidence of antibiotic resistance and the decline in the discovery of novel antibiotics have resulted in a global health crisis, particularly, for the treatment of infections caused by Gram-negative bacteria, for which therapeutic dead-ends are alarming. Here, we identify and characterize a molecule, NM102, that displays antimicrobial activity exclusively in the context of infection.

Nov 21, 2024 | nature.com | Jan Homolak |Lisa A. Maier

Entacapone, a drug used in the treatment of Parkinson’s disease, disrupts gut microbial communities by sequestering iron, creating a competitive advantage for iron-scavenging microbes that often carry antimicrobial resistance and virulence genes.

Apr 25, 2024 | healio.com | Isabella Hornick |Drew Harris |Lisa A. Maier |Kristen Dowd

You've successfully added to your alerts. You will receive an email when new content is published. Click Here to Manage Email Alerts We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Key takeaways: In a full shift, miners cannot be exposed to more than 50 μg/m3 of respirable crystalline silica. Due to the damage silica dust does to the lungs, pulmonologists said this ruling was needed to protect miners.

Sep 12, 2023 | nature.com | Lisa A. Maier

It is well known that a fibre-rich diet has beneficial effects on human health. What is less well known is that these effects are co-mediated by the gut microbiota, which converts dietary fibre into metabolites with unique physiological functions. And very few know how exactly gut microorganisms can utilize these complex carbohydrates.