Lisa M. DeCamp
Articles
Dietary Restriction Enhances CD8+ T Cell Ketolysis to Limit Exhaustion and Boost Anti-Tumor Immunity
Nov 15, 2024 |
biorxiv.org | Brandon M. Oswald |Lisa M. DeCamp |Joseph Longo |Michael S. Dahabieh
AbstractReducing calorie intake without malnutrition limits tumor progression but the underlying mechanisms are poorly understood. Here we show that dietary restriction (DR) suppresses tumor growth by enhancing CD8+ T cell-mediated anti-tumor immunity.
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