Michael S. Dahabieh

Nov 15, 2024 | biorxiv.org | Brandon M. Oswald |Lisa M. DeCamp |Joseph Longo |Michael S. Dahabieh

AbstractReducing calorie intake without malnutrition limits tumor progression but the underlying mechanisms are poorly understood. Here we show that dietary restriction (DR) suppresses tumor growth by enhancing CD8+ T cell-mediated anti-tumor immunity.

May 2, 2023 | sciencedaily.com | Michael S. Dahabieh

The protocol employs a streamlined extraction from a single sample, which reduces variation, improves efficiency, preserves data fidelity and maximizes use of precious biospecimens. "Our new technique enables researchers to study metabolic phenotypes in a unique way while getting the most information we can out of single samples," said Ryan Sheldon, Ph.D., director of VAI's Mass Spectrometry Core.

May 2, 2023 | eurekalert.org | Michael S. Dahabieh

GRAND RAPIDS, Mich. (May 2, 2023) — Van Andel Institute scientists have developed a new extraction protocol for RNA-seq and metabolomic analysis, offering a more complete picture of cellular activity than either technique on its own. The protocol employs a streamlined extraction from a single sample, which reduces variation, improves efficiency, preserves data fidelity and maximizes use of precious biospecimens.