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Integrated multi-omics analyses identify anti-viral host factors and pathways controlling SARS-CoV-2 infection - Nature Communications

Jan 1, 2024 | nature.com | Jiakai Hou |Yanjun Wei |Long Sun |Shaoheng Liang |Ashley Guerrero |Xiaobo Mao | +7 more

AbstractHost anti-viral factors are essential for controlling SARS-CoV-2 infection but remain largely unknown due to the biases of previous large-scale studies toward pro-viral host factors. To fill in this knowledge gap, we perform a genome-wide CRISPR dropout screen and integrate analyses of the multi-omics data of the CRISPR screen, genome-wide association studies, single-cell RNA-Seq, and host-virus proteins or protein/RNA interactome.
Fire | Free Full-Text | Simulation of Soil Organic Carbon Dynamics in Postfire Boreal Forests of China by Incorporating High-Resolution Remote Sensing Data and Field Measurement

Oct 26, 2023 | mdpi.com | Long Sun

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