Louis Fisher

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Articles

OpenSAFELY: The impact of COVID‐19 on azathioprine, leflunomide and methotrexate monitoring, and factors associated with change in monitoring rate

Apr 8, 2024 | bpspubs.onlinelibrary.wiley.com | Andrew Brown |Louis Fisher |Helen Curtis |Milan Wiedemann

What is already known about this subject Disease-modifying antirheumatic drugs (DMARDs) carry risks of serious adverse effects, so national guidelines recommend that patients taking them adhere to regular safety monitoring. The COVID-19 pandemic disrupted general monitoring services in England, with certain groups disproportionately affected in their health outcomes.
Eleven key measures for monitoring general practice clinical activity during COVID-19: A retrospective cohort study using 48 million adults’ primary care records in England through OpenSAFELY

Jul 27, 2023 | elifesciences.org | Louis Fisher |Helen Curtis |Richard Croker |Milan Wiedemann

We have developed 11 key measures of clinical activity and using the OpenSAFELY platform, we executed a federated analysis of changes in these measures throughout the COVID-19 pandemic, across 48 million adults registered at 6389 general practices in England. These key measures demonstrated substantial changes in clinical activity.

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