Maarten van Smeden

Dec 26, 2024 | jclinepi.com | Anum Zahra |Ewout W. Steyerberg |Rosalinde A.L. Smits |Harmke A. Polinder-Bos |Julia Minnema |Brent Appelman | +4 more

1Department of Internal Medicine, Section of Geriatrics and Gerontology, Leiden University Medical Center, Leiden, The Netherlands 2LUMC Center for Medicine for Older People, Leiden University Medical Center, Leiden, The Netherlands 3Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands 4Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Netherlands 5Division of Geriatric Medicine,...

Apr 15, 2024 | jclinepi.com | Johanna AA. Damen |Mona Ghannad |Paula Dhiman |Johannes B. Reitsma |Maarten van Smeden |Gary Collins | +3 more

This paper is only available as a PDF. To read, Please Download here. HighlightsWhat is New? •Overoptimistic reporting and misinterpretation of studies on clinical prediction models has received relatively limited attention in biomedical literature. These practices are known as ‘spin’ and are a wide phenomenon in other study designs.

Sep 29, 2023 | onlinelibrary.wiley.com | Tim Morris |Maarten van Smeden

1 INTRODUCTION Regression models frequently include covariates that were not directly measured but were calculated as functions of the directly-measured variables. An obvious example is an interaction variable, which is computed as the product of two or more measured variables. Further examples include ratios, polynomials, and other nonlinear transformations of the directly measured variables. All these cases involve some manipulation of the measured variables.

Mar 23, 2023 | ntvg.nl | Frans H Rutten |Maarten van Smeden

Elders in het NTvG staat een beknopte weergave van een onderzoek naar een model dat bedoeld is om de huisarts te helpen bij het vroegtijdig herkennen van hartfalen.1,2 Je verwacht dan een diagnostisch voorspelmodel, gebaseerd op cross-sectioneel onderzoek – dat wil zeggen: in het ‘hier en nu’ – bij mensen met klachten die hartfalen doen vermoeden. Dat was echter niet het geval.