Manuel A. Fernandez-Rojo

Apr 2, 2024 | science.org | Manuel A. Fernandez-Rojo |Amy Baek

AbstractMicroglial lipid droplet accumulation leads to increased neurotoxicity in an APOE-dependent manner. SIGN UP FOR THE SCIENCEADVISER NEWSLETTER The latest news, commentary, and research, free to your inbox daily Alzheimer’s disease (AD) is associated with the presence of lipid droplets in glial cells. The lipid metabolism–related gene APOE, particularly the presence of two copies of the APOE4 allele, is a major risk factor for AD. Haney et al.

Apr 2, 2024 | science.org | Manuel A. Fernandez-Rojo |Amy Baek |Michael A. Pearen |Anita G. Burgess

Research ArticleINFLAMMATIONManuel A. Fernandez-Rojo https://orcid.org/0000-0002-2240-1951 [email protected], Michael A. Pearen https://orcid.org/0000-0002-9401-191X, [...] , Anita G. Burgess, Maria P. Ikonomopoulou https://orcid.org/0000-0001-7739-080X, [...] , Diem Hoang-Le https://orcid.org/0009-0000-9090-8351, Berit Genz https://orcid.org/0000-0002-8038-9815, Silvia L. Saggiomo https://orcid.org/0000-0002-8228-9834, Sujeevi S. K.

Sep 4, 2023 | mdpi.com | Manuel A. Fernandez-Rojo |Tom Charlton |Bryan G. Fry |Maria P. Ikonomopoulou

Open AccessArticle by 1,†, 2,3,†, 4, 1,*,‡ and 5,6,*,‡ 1 Venom Evolution Lab, School of Biological Sciences, The University of Queensland, Brisbane, QLD 4072, Australia 2 Hepatic Regenerative Medicine Group, Madrid Institute for Advanced Studies in Food, E28049 Madrid, Spain 3 Diamantina Institute, The University of Queensland, Brisbane, QLD 4072, Australia 4 Department of Natural Sciences, Manchester Metropolitan University, All Saints Building, Manchester M15 6BH, UK 5 Translational...