Maolin Li

Oct 23, 2024 | mdpi.com | Maolin Li |Yingda Wu |Yilin Liu |Yu An Zhang

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Jul 25, 2024 | science.org | Giulia Santoni |Natalia Condic |Alice-Agnes Gabriel |Maolin Li

Editor’s summaryCarbon-fluorine bonds are notoriously scarce within naturally occurring biomolecules. Li et al. developed an enzymatic approach in which trifluoroiodoethane serves as a fluoroalkyl donor through radical addition to a vinyl arene. The enzyme uses a flavin cofactor as a chromophore, and the active site provides stereocontrol over hydrogen atom transfer to the radical intermediate.