Margaret Kielian

Oct 9, 2024 | journals.plos.org | Peiqi Yin |Albert Einstein College |Caroline Martin |Margaret Kielian |PLOS Pathogens

Fig 1. Illustration of approaches for studying virus cell-to-cell transmission in vitro and in vivo. The alphaviruses CHIKV and SINV are used as examples (panel E includes HIV). (A) Immunofluorescence microscopy illustrating ILEs. MEFs were infected with a CHIKV-GFP reporter virus for 11 h, fixed, permeabilized, and stained with antibodies to the viral envelope proteins and tubulin (micrographs are pseudo-colored and the GFP channel is not displayed). Scale bar, 20 μm.