Peiqi Yin

Jan 13, 2025 | journals.plos.org | Peiqi Yin |Albert Einstein College |Elizabeth B. Sobolik |Nicholas A. May |PLOS Pathogens

Materials and methodsThis study was performed in accordance with the recommendations in the Guide for the Care and Use of Laboratory Animals of the National Institutes of Health. Animal studies were conducted following approved institutional animal care and use committee (IACUC) protocols (#00026) of the University of Colorado School of Medicine (Assurance Number A3269-01).

Oct 9, 2024 | journals.plos.org | Peiqi Yin |Albert Einstein College |Caroline Martin |Margaret Kielian |PLOS Pathogens

Fig 1. Illustration of approaches for studying virus cell-to-cell transmission in vitro and in vivo. The alphaviruses CHIKV and SINV are used as examples (panel E includes HIV). (A) Immunofluorescence microscopy illustrating ILEs. MEFs were infected with a CHIKV-GFP reporter virus for 11 h, fixed, permeabilized, and stained with antibodies to the viral envelope proteins and tubulin (micrographs are pseudo-colored and the GFP channel is not displayed). Scale bar, 20 μm.