Margot Raffeiner

Feb 18, 2023 | cell.com | Eberhard-Karls-Universität Tübingen |Shanshuo Zhu |Margot Raffeiner |Manuel González-Fuente

HighlightsThe ubiquitin–proteasome system (UPS) and autophagy are key proteolytic pathways controlling many cellular processes, from degradation of superfluous, damaged, or misfolded proteins, to supporting development and stress responses. The complexity of the interplay between both degradation pathways is starting to be unraveled. One such example is the reciprocal turnover of their components (i.e., autophagy components degraded via the proteasome, and proteasomes recycled by autophagy).