Maria K Sobczyk

Apr 29, 2024 | medrxiv.org | Maria K Sobczyk |Tom R. Gaunt

T.R.G. receives funding from Biogen and GlaxoSmithKline for unrelated research. This work was funded by the UK Medical Research Council (MRC) as part of the MRC Integrative Epidemiology Unit (MC_UU_00032/03). This study was also supported by the NIHR Biomedical Research Centre at University Hospitals Bristol NHS Foundation Trust and the University of Bristol.

Oct 4, 2023 | nature.com | Ashley Budu-Aggrey |Anna Kilanowski |Maria K Sobczyk |Suyash Shringarpure |Ruth E. Mitchell |Kadri Reis | +68 more

AbstractAtopic dermatitis (AD) is a common inflammatory skin condition and prior genome-wide association studies (GWAS) have identified 71 associated loci. In the current study we conducted the largest AD GWAS to date (discovery N = 1,086,394, replication N = 3,604,027), combining previously reported cohorts with additional available data.

Sep 26, 2023 | bmjopen.bmj.com | Maria K Sobczyk |Jie Zheng |George Smith |Tom R. Gaunt

ResultsIn total, we found 457 254 individual studies were registered with a unique ClinicalTrials.gov identifier. We filtered them using a number of steps to identify RCTs and facilitate comparison with MR (figure 2A). In our analysis, we identified 218 506 RCT studies (48% of the total).