Marie Locard-Paulet

Jun 25, 2024 | nature.com | Henry E. Webel |Lili Niu |Marie Locard-Paulet |Matthias Mann

AbstractImputation techniques provide means to replace missing measurements with a value and are used in almost all downstream analysis of mass spectrometry (MS) based proteomics data using label-free quantification (LFQ). Here we demonstrate how collaborative filtering, denoising autoencoders, and variational autoencoders can impute missing values in the context of LFQ at different levels.