Marie Pigeyre

May 17, 2024 | nature.com | Rosie Walker |Nicolas Perrot |Marie Pigeyre |Danni A Gadd |Aleks Stolicyn |Archie Campbell | +8 more

AbstractDecline in cognitive function is the most feared aspect of ageing. Poorer midlife cognitive function is associated with increased dementia and stroke risk. The mechanisms underlying variation in cognitive function are uncertain. Here, we assessed associations between 1160 proteins’ plasma levels and two measures of cognitive function, the digit symbol substitution test (DSST) and the Montreal Cognitive Assessment in 1198 PURE-MIND participants.

Mar 27, 2024 | thelancet.com | Hertzel C. Gerstein |Marie Pigeyre

Statins cause a moderate dose-dependent increase in new diagnoses of diabetes that is consistent with a small upwards shift in glycaemia, with the majority of new diagnoses of diabetes occurring in people with baseline glycaemic markers that are close to the diagnostic threshold for diabetes.

Mar 27, 2024 | thelancet.com | Hertzel C. Gerstein |Marie Pigeyre

Statins cause a moderate dose-dependent increase in new diagnoses of diabetes that is consistent with a small upwards shift in glycaemia, with the majority of new diagnoses of diabetes occurring in people with baseline glycaemic markers that are close to the diagnostic threshold for diabetes.